Differential hybridization of amplified HpaII frangments between prostate cancer cell lines

(PC3, PC3M, PC3M-Pro4, PC3M-LN4, and LNCaP) and immortalized prostate epithelial lines (RWPE-1, 267B1 and MIcsv40)

M = increased methylation, decreased copy number, or loss of a restriction site in the cancer line.

U = increased methylation, decreased copy number, or loss of a restriction site in the immortalized line.

* = differential hybridization may be due to copy number changes

contains

PC3

PC3M

PC3M-Pro4

PC3M-LN4

LNCaP

Refseq ID

Gene Symbol

CpG island

chr

RWPE-1

267B1

Mlcsv40

RWPE-1

267B1

Mlcsv40

RWPE-1

267B1

Mlcsv40

RWPE-1

267B1

Mlcsv40

RWPE-1

267B1

Mlcsv40

Gene Description

NM_024915

FLJ13782

1

8

U*

M

M

M

M*

M*

M*

U

hypothetical protein FLJ13782

NM_015855

WIT-1

1

11

M

M

M

M

M

M

M

M

M

U

Wilms tumor associated protein

NM_014350

GG2-1

1

5

M

M

M

M

M*

M

TNF-induced protein

NM_000905

NPY

1

7

U*

M*

M

M

M

M

M

M

neuropeptide Y

NM_006142

SFN

1

1

U

U

M

U

M

U

M

M

stratifin

NM_000208

INSR

1

19

M

M

M

M

M

insulin receptor

NM_021025

TLX3

1

5

M

M

M*

M

M

M

M

M

M

M

M

T-cell leukemia, homeobox 3

NM_003206

TCF21

1

6

M

M

M

M

M

M

M

M

M

U

transcription factor 21

NM_138551

TSLP

1

5

M

M

M

M

M

M

M

M

M

M

M

M

M

thymic stromal lymphopoietin

NM_024501

HOXD1

1

2

M

M

M

M

M

M

M

M

M

M

M

M

M

homeo box D1

NM_003118

SPARC

0

5

M

M

M

M

M

M

M

M

M

M

M

secreted protein, acidic, cysteine-rich (osteonectin)

NM_052860

ZNF300

1

5

M

zinc finger protein 300

NM_001482

GATM

1

15

M

M

M

M

M

M

glycine amidinotransferase (L-arginine:glycine amidinotransferase)

NM_017902

HIF1AN

0

10

M*

M*

M*

M

M

hypoxia-inducible factor 1, alpha subunit inhibitor

NM_017790

RGS3

0

9

M

M

M

M

regulator of G-protein signalling 3 isoform 3

NM_001538

HSF4

1

16

M

M

M

M

M

M

M

heat shock transcription factor 4

NM_005593

MYF5

1

12

M

M

M

M

M

M

M

myogenic factor 5

NM_007105

SLC22A1LS

0

11

M

M

solute carrier family 22 (organic cation transporter), member 1-like antisense

NM_024331

C20orf121

1

20

M

M*

M

M

M

chromosome 20 open reading frame 121

NM_003529

HIST1H3A

1

6

M

M

M

M

M

M*

M*

M*

H3 histone family, member A

NM_004419

DUSP5

1

10

M

M

M

dual specificity phosphatase 5

NM_005599

NHLH2

1

1

M

M

nescient helix loop helix 2

NM_018294

FLJ10998

1

10

M

M

M*

M

hypothetical protein FLJ10998

NM_020796

SEMA6A

1

5

M

M

M

M

M

M

M

M*

semaphorin 6A1

NM_025002

FLJ13162

1

6

M

M

M

M

hypothetical protein FLJ13162

NM_145285

NKX2-3

1

10

M*

M

NK2 transcription factor related, locus 3 (Drosophila)

NM_020168

PAK6

1

15

M

M

M*

p21-activated protein kinase 6

NM_022755

C9orf12

1

9

M

M*

M*

chromosome 9 open reading frame 12

NM_017824

FLJ20445

1

10

M

M*

hypothetical protein FLJ20445

NM_183401

RNF14

1

5

M*

ring finger protein 14

NM_017614

BHMT2

1

5

M*

M*

betaine-homocysteine methyltransferase 2

NM_001790

CDC25C

1

5

M*

cell division cycle 25C protein, isoform a

NM_052841

STK22C

1

1

M

serine/threonine kinase 22C (spermiogenesis associated)

NM_031437

RASSF5

1

1

U

Ras association (RalGDS/AF-6) domain family 5

NM_003222

TFAP2C

1

20

M*

M*

transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

NM_004878

PTGES

0

9

M

M

M

prostaglandin E synthase

NM_000043

TNFRSF6

1

10

M

M

M*

M

tumor necrosis factor receptor superfamily, member 6 isoform 1 precursor

NM_032783

FLJ14431

1

4

M*

hypothetical protein FLJ14431

NM_003177

SYK

1

9

M*

spleen tyrosine kinase

NM_014003

DHX38

1

16

M

M

pre-mRNA splicing factor Prp16

NM_003791

MBTPS1

1

16

M

M

site-1 protease preproprotein

NM_004125

GNG10

1

9

M

guanine nucleotide binding protein (G protein), gamma 10

NM_020121

UGCGL2

1

13

M

M*

UDP-glucose:glycoprotein glucosyltransferase 2

NM_030971

BA108L7.2

1

10

M*

M*

M

similar to rat tricarboxylate carrier-like protein

NM_000138

FBN1

1

15

M

M

M*

M*

M

M

M

fibrillin 1

NM_018197

ZFP64

1

20

M

M*

M*

M

M*

M*

M*

zinc finger protein 64

NM_002052

GATA4

1

8

M

M

M

M

M

M

M

GATA binding protein 4

NM_025264

C2orf8

1

2

M

M

hypothetical protein MGC2454

NM_080652

MGC15397

1

3

M

M

M

similar to RIKEN cDNA 5730578N08 gene

NM_005165

ALDOC

0

17

U

aldolase C, fructose-bisphosphate

NM_144503

F11R

1

1

M

M

M

M

M

M

junctional adhesion molecule 1 isoform a precursor

NM_006898

HOXD3

1

2

M

M

M

M

M

M

M

M

M

homeo box D3

NM_016733

LIMK2

0

22

M

M

M

M

M

LIM domain kinase 2 isoform 2b

NM_006871

RIPK3

1

14

M

M

receptor-interacting serine-threonine kinase 3

NM_014080

DUOX2

1

15

M

M

M

M

M

M

M

M

dual oxidase 2

NM_052918

SORCS1

1

10

M*

M*

M

M

M

M

sortilin-related VPS10 domain containing receptor 1

NM_002110

HCK

1

20

M*

M*

M*

M*

M*

M*

M

M*

M*

M*

M*

hemopoietic cell kinase

NM_000441

SLC26A4

1

7

M

M

M

M

M

M

M

M

M

pendrin

NM_004817

TJP2

1

9

M

M

M*

M

M

M*

M

M

tight junction protein 2 (zona occludens 2)

NM_021828

HPSE2

0

10

M

M*

M

M

M*

heparanase 2

NM_003780

B4GALT2

0

1

M

M

M

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2 isoform b

NM_001374

DNASE1L2

1

16

M

M

M

M

M

deoxyribonuclease I-like 2

NM_021154

PSAT1

1

9

M

M

phosphoserine aminotransferase isoform 2

NM_002202

ISL1

1

5

M

M

M*

M

M

islet-1

NM_002084

GPX3

1

5

M

M*

M

M

M*

plasma glutathione peroxidase 3 precursor

NM_004523

KIF11

1

10

M

M

M

M

M

M*

kinesin family member 11

NM_012449

STEAP

1

7

M

M

M

M

M

M

M

six transmembrane epithelial antigen of the prostate

NM_033028

BBS4

1

15

M

M*

M

M

M

M

M

M

Bardet-Biedl syndrome 4

NM_004647

DPF1

1

19

M

M

Neuro-d4 (rat) homolog

NM_000125

ESR1

1

6

M

estrogen receptor 1

NM_005732

RAD50

1

5

M

M*

M

M

M

M

M

M

RAD50 homolog isoform 1

NM_021967

SERF1A

1

5

M*

M*

small EDRK-rich factor 1A (telomeric)

NM_022145

FKSG14

1

5

M*

M*

M*

M*

M*

M*

leucine zipper protein FKSG14

NM_133338

RAD17

1

5

M*

M*

M*

M*

RAD17 homolog isoform 1

NM_133342

RAD17

1

5

M*

M*

M*

M*

RAD17 homolog isoform 1

NM_153713

MGC46719

1

1

M

M

M

M

hypothetical protein MGC46719

NM_003308

TSPY

1

Y

M*

M*

M*

M*

M*

M*

M*

M*

U*

testis specific protein, Y-linked

NM_022573

TSPYQ1

0

Y

M*

M*

M*

M*

M*

M*

M*

M*

U*

testis specific protein, Y-linked 2

NM_002467

MYC

1

8

U*

U*

U

U

U

U

U

U*

U*

U*

U*

v-myc myelocytomatosis viral oncogene homolog

NM_018071

FLJ10357

0

14

U

U

U

U

U

hypothetical protein FLJ10357

NM_002578

PAK3

0

X

U

U

U

U*

U*

U*

U

U*

U*

p21-activated kinase 3

NM_004535

MYT1

0

20

U

U

U

U

myelin transcription factor 1

NM_015460

MYRIP

1

3

U*

U

U

U

U*

U

U*

U

M

myosin VIIA and Rab interacting protein

NM_005362

MAGEA3

1

X

U

U

U

U

U

U

melanoma antigen, family A, 3

NM_032804

FLJ14547

1

10

U

U*

U*

U

U

U

U*

U*

U

U*

U*

hypothetical protein FLJ14547

NM_003762

VAMP4

1

1

U

U

U

U

U

U

U

U

U

U

U

vesicle-associated membrane protein 4

NM_030759

NRBF-2

1

10

U

U*

U*

nuclear receptor binding factor-2

NM_014951

ZNF365

1

10

U

U*

U*

U

U

U*

U*

U

U*

U*

KIAA0844 protein

NM_002658

PLAU

1

10

U

U

U*

U

U

U

U

U*

U*

U

U

U*

plasminogen activator, urokinase

NM_007055

RPC155

1

10

U

U

U

U

U

U

U

U

U

M*

M*

M*

polymerase (RNA) III (DNA directed) polypeptide A, 155kDa

NM_005822

DSCR1L1

0

6

M

M*

Down syndrome critical region gene 1-like 1 protein

NM_018649

H2AFY2

1

10

U*

U

U

U*

M

core histone macroH2A2.2

NM_003242

TGFBR2

1

3

U*

M

M

M

transforming growth factor, beta receptor II (70/80kDa)

NM_021614

KCNN2

1

5

U

U

U

small conductance calcium-activated potassium channel protein 2 isoform a

NM_003591

CUL2

1

10

U

U

U

cullin 2

NM_017444

CHRAC1

1

8

U*

U*

U*

chromatin accessibility complex 1

NM_018444

PPM2C

1

8

U*

U*

U*

pyruvate dehydrogenase phosphatase

NM_001642

APLP2

1

11

U*

U*

U*

amyloid beta (A4) precursor-like protein 2

NM_016077

CGI-147

1

17

U

CGI-147 protein

NM_022831

FLJ12806

1

1

U

U

U

hypothetical protein FLJ12806

NM_018186

FLJ10706

1

1

U

U

U

hypothetical protein FLJ10706

NM_016026

RDH11

0

14

U*

U*

U*

androgen-regulated short-chain dehydrogenase/reductase 1

NM_006019

TCIRG1

1

11

U

U

U

T-cell, immune regulator 1, isoform a

NM_006888

CALM1

1

14

U

U

calmodulin 1 (phosphorylase kinase, delta)

NM_003744

NUMB

1

14

U

U*

U*

numb homolog

NM_006255

PRKCH

1

14

U*

U*

U*

protein kinase C, eta

NM_004702

CCNE2

1

8

U*

U*

cyclin E2 isoform 3

NM_021052

HIST1H2AE

1

6

M*

H2A histone family, member A

NM_138635

H2AV

1

7

U

histone H2A.F/Z variant isoform 2

NM_004282

BAG2

1

6

M*

M*

BCL2-associated athanogene 2

NM_021064

HIST1H2AG

1

6

M*

H2A histone family, member P

NM_019014

POLR1B

1

2

M

M

similar to DNA-directed RNA polymerase I (135 kDa)

NM_013324

CISH

1

3

U

U

cytokine-inducible SH2-containing protein isoform 1

NM_144695

FLJ32421

1

1

U

hypothetical protein FLJ32421

NM_016023

CGI-77

1

8

U*

U*

CGI-77 protein

NM_007057

ZWINT

1

10

U*

U*

ZW10 interactor

NM_002290

LAMA4

1

6

U

U

U

laminin, alpha 4 precursor

NM_016249

MAGEE1

0

X

U

U

U*

melanoma antigen, family E, 1, cancer/testis specific

NM_001607

ACAA1

1

3

U*

acetyl-Coenzyme A acyltransferase 1

NM_022461

AZ2

1

3

U*

hypothetical protein FLJ21939 similar to 5-azacytidine induced gene 2

NM_025010

KIAA0795

1

3

U*

hypothetical protein FLJ13703

NM_003666

BLZF1

0

1

U

basic leucine zipper nuclear factor 1 (JEM-1)

NM_013374

PDCD6IP

1

3

U*

programmed cell death 6 interacting protein

NM_006840

LILRB5

0

19

U

U

U

U

U

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5

NM_003373

VCL

1

10

U

U

U

U

vinculin isoform VCL

NM_000486

AQP2

0

12

U

U

U*

aquaporin 2

NM_004693

K6HF

0

12

U

U

U*

U

U

U

cytokeratin type II

NM_020634

GDF3

0

12

U

U

U

growth differentiation factor 3 precursor

NM_002644

PIGR

0

1

U

U

U

polymeric immunoglobulin receptor

NM_000497

CYP11B1

0

8

U*

U*

U

U

cytochrome P450, family 11, subfamily B, polypeptide 1

NM_002814

PSMD10

1

X

U

U*

proteasome 26S non-ATPase subunit 10 isoform 1

NM_001674

ATF3

1

1

U

U

U

activating transcription factor 3 long isoform

NM_021029

RPL36A

1

X

U

U

U

ribosomal protein L36a

NM_018972

GDAP1

1

8

U*

ganglioside-induced differentiation-associated protein 1

NM_000858

GUK1

1

1

U

U

U

U

guanylate kinase 1

NM_004024

ATF3

1

1

U

U

U

activating transcription factor 3 delta Zip isoform

NM_018099

FLJ10462

0

12

U

U

hypothetical protein FLJ10462

NM_000124

ERCC6

1

10

U

excision repair cross-complementing rodent repair deficiency, complementation group 6

NM_001123

ADK

1

10

U

U

U

adenosine kinase isoform a

NM_007265

HSGT1

1

10

U

U

U*

U*

U

U*

suppressor of S. cerevisiae gcr2

NM_005329

HAS3

1

16

U

U

hyaluronan synthase 3

NM_023032

METTL1

1

12

U

U

methyltransferase-like protein 1 isoform b

NM_023033

METTL1

1

12

U

U

U

methyltransferase-like protein 1 isoform c

NM_021222

HTCD37

1

1

M

M

TcD37 homolog

NM_001452

FOXF2

1

6

U

U

U

forkhead box F2

NM_000641

IL11

0

19

M

M

U

U

interleukin 11 precursor

NM_014213

HOXD9

1

2

U

homeo box D9

NM_005557

KRT16

0

17

U

U

keratin 16

NM_004314

ART1

0

11

U

ADP-ribosyltransferase 1

NM_004681

EIF1AY

1

Y

M

M*

eukaryotic translation initiation factor 1A, Y chromosome

NM_016124

RHD

0

1

U

U

U

U

Rh blood group D antigen isoform 1

NM_021193

HOXD12

1

2

U

homeo box D12

NM_020314

MGC16824

1

16

U

esophageal cancer associated protein

NM_003307

TRPM2

0

21

U

transient receptor potential cation channel, subfamily M, member 2

NM_005432

XRCC3

1

14

U

X-ray repair cross complementing protein 3

NM_015250

BICD2

1

9

U*

coiled-coil protein BICD2

NM_006783

GJB6

0

13

U*

gap junction protein, beta 6 (connexin 30)

NM_139209

GPRK7

1

3

U

U

U

G protein-coupled receptor kinase 7

NM_004264

SURB7

1

12

U

SRB7 suppressor of RNA polymerase B homolog

NM_000224

KRT18

1

12

U

U

U

keratin 18

NM_006106

YAP1

1

11

U

U

Yes-associated protein 1, 65 kD

NM_152879

DGKD

0

2

U

diacylglycerol kinase, delta 130kDa isoform 2

NM_145254

LOC124491

1

16

U

LOC124491

NM_153259

MCOLN2

1

1

U

mucolipin 2

NM_005940

MMP11

1

22

U

matrix metalloproteinase 11 preproprotein

NM_014409

TAF5L

1

1

U

PCAF associated factor 65 beta

NM_080605

B3GALT6

0

1

U

U

UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6

NM_024012

HTR5A

1

7

U

U

5-hydroxytryptamine (serotonin) receptor 5A

NM_021106

RGS3

0

9

U

U

regulator of G-protein signalling 3 isoform 2

NM_001327

CTAG1

0

X

U

U

U

U

U

U

U

U

U

cancer/testis antigen 1

NM_020177

FEM1C

0

5

U

U

U

U*

feminization 1 homolog a

NM_025228

DJ434O14.3

0

1

U

U

U

U

U

U

hypothetical protein dJ434O14.3

NM_004679

VCY

0

Y

U*

U

U

U*

U

U*

U*

U

U

variable charge, Y chromosome

NM_017745

BCOR

1

X

U

U

U

BCL-6 interacting corepressor isoform 1

NM_014345

ZNF318

1

6

U

U

U

endocrine regulator

NM_005597

NFIC

1

19

U

U

U

nuclear factor I/C (CCAAT-binding transcription factor)

NM_006206

PDGFRA

1

4

U

U

platelet-derived growth factor receptor alpha precursor

NM_015686

TED

1

X

U

U

TED protein

NM_001772

CD33

0

19

U

CD33 antigen (gp67)

NM_018968

SNTG2

0

2_random

U

syntrophin, gamma 2

NM_015120

ALMS1

1

2

U

U

ALMS1

NM_000276

OCRL

1

X

U

phosphatidylinositol polyphosphate 5-phosphatase isoform a

NM_001587

OCRL

1

X

U

U

U

U

phosphatidylinositol polyphosphate 5-phosphotase isoform b

NM_144488

RGS3

0

9

U

U

regulator of G-protein signalling 3 isoform 6

NM_138455

CTHRC1

1

8

U*

U

U

U*

U*

U*

U

collagen triple helix repeat containing 1

NM_005554

KRT6A

0

12

U

U

keratin 6A

NM_014865

CNAP1

1

12

M

M

U

M

chromosome condensation-related SMC-associated protein 1

NM_002447

MST1R

1

3

U

U

U

M

macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

NM_032312

MGC11061

1

2

U

hypothetical protein MGC11061

NM_000760

CSF3R

0

1

U

U

U

U

colony stimulating factor 3 receptor isoform a precursor

NM_001715

BLK

0

8

U

B lymphoid tyrosine kinase

NM_000061

BTK

0

X

U

U

Bruton agammaglobulinemia tyrosine kinase

NM_005555

KRT6B

0

12

U

U

keratin 6B

NM_139073

TSARG1

0

2

U

U

U

U

U

spermatogenesis associated 3

NM_000728

CALCB

1

11

U

U

calcitonin-related polypeptide, beta

NM_016323

CEB1

1

4

U

cyclin-E binding protein 1

NM_002952

RPS2

1

16

U

U

U

ribosomal protein S2

NM_024090

ELOVL6

1

4

U

long-chain fatty-acyl elongase

NM_017877

FLJ20555

1

2

U

hypothetical protein FLJ20555

NM_014353

RAB26

1

16

U

RAB26, member RAS oncogene family

NM_032960

MAPKAPK2

1

1

U

mitogen-activated protein kinase-activated protein kinase 2 isoform 2

NM_018958

C15orf2

1

15

U*

chromosome 15 open reading frame 2

NM_003332

TYROBP

0

19

U

U

U

TYRO protein tyrosine kinase binding protein

NM_016478

NIPA

1

7

U

nuclear interacting partner of anaplastic lymphoma kinase (ALK)

NM_007110

TEP1

1

14

U

telomerase-associated protein 1

NM_003043

SLC6A6

0

3

U

U

solute carrier family 6 (neurotransmitter transporter, taurine), member 6

NM_002162

ICAM3

0

19

U

U

U

intercellular adhesion molecule 3 precursor

NM_002762

PRM2

1

16

U

U

U

protamine 2

NM_007155

ZP3

0

7

U

zona pellucida glycoprotein 3 (sperm receptor)

NM_003636

KCNAB2

1

1

M

U

U

potassium voltage-gated channel, shaker-related subfamily, beta member 2 isoform 1

NM_014621

HOXD4

1

2

M

homeo box D4

NM_000964

RARA

0

17

U

retinoic acid receptor, alpha

NM_015277

NEDD4L

1

18

M*

U*

ubiquitin-protein ligase NEDD4-like

NM_000657

BCL2

1

18

M*

B-cell lymphoma protein 2 beta

NM_052861

MGC21675

1

4

M

hypothetical protein MGC21675

NM_005203

COL13A1

1

10

U*

U*

M*

alpha 1 type XIII collagen isoform 1

NM_019616

F7

0

13

U*

M

coagulation factor VII precursor isoform b

NM_017918

FLJ20647

1

4

U

hypothetical protein FLJ20647

NM_000585

IL15

1

4

U*

U

U*

interleukin 15 isoform 1 precursor

NM_003601

SMARCA5

1

4

U

U

U*

M

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a5

NM_004362

CLGN

1

4

U

U*

calmegin

NM_000788

DCK

1

4

U

U

deoxycytidine kinase

NM_007292

ACOX1

1

17

U

U*

acyl-Coenzyme A oxidase isoform b

NM_002129

HMGB2

1

4

U*

U*

high-mobility group box 2

NM_003878

GGH

1

8

U*

gamma-glutamyl hydrolase precursor

NM_003631

PARG

1

10

U

poly (ADP-ribose) glycohydrolase

NM_018089

FLJ10415

1

2

U

U

hypothetical protein FLJ10415

NM_000543

SMPD1

1

11

U

sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingom

NM_021184

C6orf47

0

6

U

G4 protein

NM_007254

PNKP

1

19

U

U

U

polynucleotide kinase 3'-phosphatase

NM_018396

METTL2

1

7

U

putative methyltransferase

NM_004907

ETR101

1

19

U

immediate early protein

NM_007067

MYST2

1

17

U

U

U

histone acetyltransferase

NM_004187

SMCX

1

X

U

Smcx homolog, X chromosome

NM_016114

ASB1

1

2

U

U

U

ankyrin repeat and SOCS box-containing protein 1

NM_005637

SS18

1

18

U*

U

synovial sarcoma, translocated to X chromosome

NM_016406

HSPC155

0

1

U

U

hypothetical protein HSPC155

NM_006212

PFKFB2

1

1

U

U

U

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

NM_000938

POLR2B

1

4

U

U

U*

U

DNA directed RNA polymerase II polypeptide B

NM_004337

C8orf1

1

8

U*

U*

U

U*

chromosome 8 open reading frame 1

NM_002485

NBS1

1

8

U*

U*

nibrin

NM_014109

PRO2000

1

8

U*

U*

U*

PRO2000 protein

NM_024094

MGC5528

1

8

U*

U*

U*

hypothetical protein MGC5528

NM_019069

WDR5B

0

3

U

U

U

U

WD repeat domain 5B

NM_005081

ZNF142

1

2

U

U

zinc finger protein 142 (clone pHZ-49)

NM_020806

GPHN

1

14

U*

U*

U*

gephyrin

NM_001530

HIF1A

1

14

U*

U*

U*

hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

NM_006544

SEC10L1

1

14

U*

U*

U*

brain secretory protein SEC10P

NM_031866

FZD8

0

10

U

U

U

frizzled homolog 8 (Drosophila)

NM_012320

LYPLA3

1

16

U

lysophospholipase 3 (lysosomal phospholipase A2)

NM_016551

TM7SF3

1

12

U

U

U

M

seven transmembrane protein TM7SF3

NM_032795

FLJ14494

1

11

U*

hypothetical protein FLJ14494

NM_007086

AND-1

1

14

U*

U*

AND-1 protein

NM_014039

PTD012

1

11

U

PTD012 protein

NM_001786

CDC2

1

10

U*

U*

cell division cycle 2 protein isoform 1

NM_005387

NUP98

1

11

U

nucleoporin 98kD isoform 3

NM_006328

RBM14

1

11

U

RNA binding motif protein 14

NM_003478

CUL5

1

11

U*

Vasopressin-activated calcium-mobilizing receptor-1

NM_032118

FLJ12953

1

2

U

U

hypothetical protein FLJ12953 similar to Mus musculus D3Mm3e

NM_003201

TFAM

1

10

U*

U*

U*

transcription factor A, mitochondrial

NM_024604

FLJ21908

1

12

U

hypothetical protein FLJ21908

NM_006338

GAC1

1

1

U

U

glioma amplified on chromosome 1 protein (leucine-rich)

NM_004260

RECQL4

1

8

U

RecQ protein-like 4

NM_012482

ZNF281

1

1

U

U

zinc finger protein 281

NM_007276

CBX3

1

7

U

U*

U

chromobox homolog 3

NM_004398

DDX10

1

11

U*

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 10

NM_005613

RGS4

0

1

U

regulator of G-protein signaling 4

NM_014002

IKBKE

0

1

U

IKK-related kinase epsilon

NM_030813

SKD3

1

11

U

suppressor of potassium transport defect 3

NM_003936

CDK5R2

1

2

U

cyclin-dependent kinase 5, regulatory subunit 2 (p39)

NM_021144

PSIP2

1

9

U

PC4 and SFRS1 interacting protein 1

NM_145258

MGC22773

1

1

U

hypothetical protein MGC22773

NM_017769

FLJ20333

1

14

U

KIAA1333

NM_030631

SLC25A21

1

14

U

U

solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21

NM_003582

DYRK3

1

1

U

U

U

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3

NM_145117

NAV2

1

11

U

neuron navigator 2 isoform L

NM_004328

BCS1L

1

2

U

BCS1-like

NM_020247

CABC1

1

1

U

U

chaperone, ABC1 activity of bc1 complex like

NM_001087

AAMP

1

2

U

angio-associated, migratory cell protein

NM_015488

MR-1

1

2

U

U

U

U

myofibrillogenesis regulator 1

NM_000447

PSEN2

1

1

U

U

presenilin 2 isoform 1

NM_006706

TCERG1

1

5

U

transcription elongation regulator 1

NM_006704

SUGT1

1

13

M

SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)

NM_015132

SNX13

1

7

U*

U

sorting nexin 13

NM_024728

C7orf10

1

7

U

chromosome 7 open reading frame 10

NM_001912

CTSL

1

9

U

cathepsin L preproprotein

NM_145918

CTSL

1

9

U

cathepsin L preproprotein

NM_024035

MGC3113

0

8

U*

U

U

hypothetical protein MGC3113

NM_004195

TNFRSF18

1

1

U

tumor necrosis factor receptor superfamily, member 18

NM_148901

TNFRSF18

1

1

U

U

U

U

tumor necrosis factor receptor superfamily, member 18

NM_003999

OSMR

1

5

M

M

M

M

oncostatin M receptor

NM_024558

C14orf138

1

14

M

M

M

hypothetical protein FLJ13920

NM_003445

ZNF155

0

19

M

M

M

M

zinc finger protein 155 (pHZ-96)

NM_022771

FLJ12085

1

12

U

M

M

M

hypothetical protein FLJ12085

NM_004172

SLC1A3

0

5

M

M

M

M

M

solute carrier family 1 (glial high affinity glutamate transporter), member 3

NM_012382

OSRF

1

5

M*

M

M

M

osmosis responsive factor

NM_005983

SKP2

1

5

M

M

M

M

S-phase kinase-associated protein 2 isoform 1

NM_032637

SKP2

1

5

M

M

M

M

S-phase kinase-associated protein 2 isoform 2

NM_032933

MGC11386

0

18

U*

U

hypothetical protein MGC11386

NM_013978

BNIP1

0

5

U

BCL2/adenovirus E1B 19kD interacting protein 1 isoform BNIP1-a

NM_006168

NKX6-1

1

4

M

U*

NK6 transcription factor related, locus 1

NM_080683

PTPN13

1

4

U*

protein tyrosine phosphatase, non-receptor type 13 isoform 1

NM_004433

ELF3

0

1

M

M

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

NM_000347

SPTB

1

14

M

spectrin, beta, erythrocytic (includes spherocytosis, clinical type I)

NM_018951

HOXA10

1

7

U*

U

U

homeobox protein A10 isoform a

NM_002501

NFIX

1

19

U

U

U

U

nuclear factor I/X (CCAAT-binding transcription factor)

NM_004642

CDK2AP1

1

12

U

M

M

M

M

M

M

CDK2-associated protein 1

NM_014586

HUNK

1

21

U

M

M

M

hormonally upregulated Neu-associated kinase

NM_014644

PDE4DIP

0

1

U

M

M

M

M

phosphodiesterase 4D interacting protein (myomegalin)

NM_007173

SPUVE

1

11

M

M

M

M

M

protease, serine, 23 precursor

NM_022492

FLJ12788

1

2

M

M

M

hypothetical protein FLJ12788

NM_000389

CDKN1A

1

6

M

M

M

cyclin-dependent kinase inhibitor 1A

NM_001924

GADD45A

1

1

M

M

M

growth arrest and DNA-damage-inducible, alpha

NM_024963

FLJ11467

1

7

U

hypothetical protein FLJ11467

NM_013248

NXT1

1

20

U

NTF2-related export protein 1

NM_052865

C20orf72

1

20

M*

M*

chromosome 20 open reading frame 72

NM_014660

PHF14

1

7

M*

M

M*

M

KIAA0783 gene product

NM_017410

HOXC13

1

12

M

M*

homeo box C13

NM_000082

CKN1

1

5

M*

M*

M

M*

M

M

Cockayne syndrome 1 protein

NM_002451

MTAP

1

9

M

M

M

M

5'-methylthioadenosine phosphorylase

NM_003525

HIST1H2BI

1

6

M*

M*

H2B histone family, member K

NM_002165

ID1

1

20

M*

M*

M*

M*

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

NM_003640

IKBKAP

1

9

M

M

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein

NM_006020

ALKBH

1

14

M

M

M

alkB, alkylation repair homolog

NM_002486

NCBP1

1

9

M*

nuclear cap binding protein subunit 1, 80kDa

NM_005184

CALM3

1

19

M

M

calmodulin 3 (phosphorylase kinase, delta)

NM_002874

RAD23B

1

9

M

M

UV excision repair protein RAD23 homolog B

NM_000227

LAMA3

0

18

U*

laminin alpha 3 subunit precursor

NM_003930

SCAP2

1

7

U*

src family associated phosphoprotein 2

NM_016265

ZNF325

1

7

U*

M*

GIOT-3 for gonadotropin inducible transcription repressor-3

NM_012153

EHF

0

11

U

ets homologous factor isoform b

NM_000790

DDC

0

7

M

M

dopa decarboxylase (aromatic L-amino acid decarboxylase)

NM_130470

MADD

1

11

M

MAP-kinase activating death domain-containing protein, isoform a

NM_003001

SDHC

1

1

U

U

succinate dehydrogenase complex, subunit C precursor

NM_003775

EDG6

1

19

U

U

endothelial differentiation, G protein coupled receptor 6 precursor

NM_012385

P8

0

16

U

U

U

p8 protein (candidate of metastasis 1)

NM_000882

IL12A

1

3

U

interleukin 12A precursor

NM_004165

RRAD

1

16

U

U

U

Ras-related associated with diabetes

NM_147129

FLJ36525

1

3

U

hypothetical protein LOC259173

NM_003120

SPI1

1

11

U

spleen focus forming virus (SFFV) proviral integration oncogene spi1

NM_000417

IL2RA

0

10

U

interleukin 2 receptor, alpha chain precursor

NM_016113

TRPV2

0

17

U

transient receptor potential cation channel, subfamily V, member 2

NM_032128

DKFZP566M114

1

4

M

M

M

Homo sapiens hypothetical protein DKFZp566M114 (DKFZP566M114)

NM_007285

GABARAPL2

1

16

M

M

M

GABA(A) receptor-associated protein-like 2

NM_022041

GAN

1

16

M

M

M

gigaxonin

NM_001839

CNN3

1

1

M

M

M

calponin 3

NM_014324

AMACR

1

5

M

alpha-methylacyl-CoA racemase

NM_017761

FLJ20312

1

1_random

M

M

M

hypothetical protein FLJ20312

NM_138284

IL17D

1

13

M

M*

M*

M*

interleukin 17D

NM_004875

POLR1C

1

6

M

M

M

RNA polymerase I subunit

NM_006479

PIR51

1

12

M

M

M

M

M

RAD51-interacting protein

NM_005996

TBX3

1

12

M

M

M

M

M

T-box 3 protein isoform 1

NM_032380

EFG2

1

5

M*

M*

mitochondrial elongation factor G2

NM_006041

HS3ST3B1

1

17

M

heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1

NM_002749

MAPK7

1

17

M

mitogen-activated protein kinase 7 isoform 1

NM_006169

NNMT

0

11

M*

M

M

nicotinamide N-methyltransferase

NM_018064

C6orf166

1

6

M*

M*

hypothetical protein FLJ10342

NM_005548

KARS

1

16

M

lysyl-tRNA synthetase

NM_138343

KNSL8

1

6

M

kinesin-like 8

NM_024979

MCF2L

1

13

M

MCF.2 cell line derived transforming sequence-like

NM_024010

MTRR

1

5

M

methionine synthase reductase isoform 2

NM_032087

PCDHGA7

1

5

M

protocadherin gamma subfamily A, 1

NM_000965

RARB

0

3

M

retinoic acid receptor, beta isoform 1

NM_002033

FUT4

1

11

U*

M

fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)

NM_000177

GSN

1

9

U

gelsolin (amyloidosis, Finnish type)

NM_032872

JFC1

0

1

U

synaptotagmin-like 1

NM_004659

MMP23A

1

1

U

matrix metalloproteinase 23A

NM_182649

PCNA

1

20

U

proliferating cell nuclear antigen

NM_001116

ADCY9

0

16

M

adenylate cyclase 9

NM_024758

AGMAT

1

1

U

agmatine ureohydrolase (agmatinase)

NM_006092

CARD4

1

7

M

caspase recruitment domain family, member 4

NM_003818

CDS2

1

20

U

phosphatidate cytidylyltransferase 2

NM_024668

FLJ20288

1

5

M

M

FLJ20288 protein

NM_004899

BRE

1

2

M

brain and reproductive organ-expressed (TNFRSF1A modulator)

NM_001902

CTH

1

1

M

cystathionase isoform 1

NM_004048

B2M

1

15

M

beta-2-microglobulin

NM_021824

NIF3L1

0

2

M

NIF3 NGG1 interacting factor 3-like 1

NM_004888

ATP6V1G1

1

9

M

M

ATPase, H+ transporting, lysosomal, V1 subunit G isoform 1

NM_002946

RPA2

1

1

M

M

replication protein A2, 32kDa

NM_014229

SLC6A11

1

3

U

solute carrier family 6 (neurotransmitter transporter, GABA), member 11

NM_001516

GTF2H3

1

12

M

general transcription factor IIH, polypeptide 3, 34kDa

NM_002097

GTF3A

1

13

M

general transcription factor IIIA

NM_144706

MGC29762

1

2

M

chromosome 2 open reading frame 15

NM_006158

NEFL

1

8

M

M

neurofilament, light polypeptide 68kDa

NM_006194

PAX9

1

14

M

paired box gene 9

NM_012243

SLC35A3

1

1

M

solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3

NM_014174

THY28

1

11

M

HSPC144 protein

NM_017779

FLJ20354

1

1

M

M

M

hypothetical protein FLJ20354

NM_032673

NSPC1

1

2

M

M

hypothetical protein MGC10882

NM_006086

TUBB4

1

16

M

tubulin, beta, 4

NM_005211

CSF1R

0

5

M

M

M

M

M

colony stimulating factor 1 receptor precursor

NM_003532

HIST1H3E

1

6

M

M*

M

M

M

M

M

M

M*

M*

M*

H3 histone family, member D

NM_153038

FLJ32447

1

2

M

M

hypothetical protein FLJ32447

NM_003740

KCNK5

1

6

M

M

M

M

potassium channel, subfamily K, member 5

NM_005098

MSC

1

8

M

M

musculin (activated B-cell factor-1)

NM_005806

OLIG2

1

21

M*

oligodendrocyte lineage transcription factor 2

NM_003542

HIST1H4C

1

6

M*

M*

H4 histone family, member G

NM_022164

LCN7

0

1

M

M

M

M

P3ECSL

NM_006021

DLEU2

1

13

M

M

deleted in lymphocytic leukemia, 2

NM_000926

PGR

1

11

M

progesterone receptor

NM_004472

FOXD1

0

5

M*

M

M*

forkhead box D1

NM_024296

MGC1203

1

1

M

hypothetical protein MGC1203

NM_145805

ISL2

1

15

M

M

M

M

ISL2 transcription factor, LIM/homeodomain, (islet-2)

NM_004330

BNIP2

1

15

M

BCL2/adenovirus E1B 19kD interacting protein 2

NM_002757

MAP2K5

1

15

M*

mitogen-activated protein kinase kinase 5 isoform B

NM_018163

FLJ10634

1

15

M

M

M

hypothetical protein FLJ10634

NM_000985

RPL17

1

18

M

M

M

ribosomal protein L17

NM_014978

SORCS3

1

10

M

VPS10 domain receptor protein SORCS 3

NM_004701

CCNB2

1

15

M

M

M*

M

M

M

M

M

M

cyclin B2

NM_014262

LEPREL2

1

12

M

M

M

M

M

B protein

NM_183001

SHC1

0

1

M

M

M

SHC (Src homology 2 domain containing) transforming protein 1

NM_000546

TP53

1

17

M

M

M

M

M

tumor protein p53

NM_004730

ETF1

1

5

M

eukaryotic translation termination factor 1

NM_002082

GPRK6

1

5

U

M

G protein-coupled receptor kinase 6

NM_002520

NPM1

1

5

U

M

M

nucleophosmin (nucleolar phosphoprotein B23, numatrin)

NM_003291

TPP2

1

13

M

tripeptidyl peptidase II

NM_000024

ADRB2

1

5

M

adrenergic, beta-2-, receptor, surface

NM_004627

WRB

1

21

U*

tryptophan rich basic protein

NM_006732

FOSB

1

19

M

M

FBJ murine osteosarcoma viral oncogene homolog B

NM_014335

CRI1

1

15

M*

M

M

CREBBP/EP300 inhibitory protein 1

NM_004663

RAB11A

1

15

M*

M*

M*

RAB11A, member RAS oncogene family

NM_003524

HIST1H2BH

1

6

M*

M*

H2B histone family, member J

NM_006547

IMP-3

1

7

M

IGF-II mRNA-binding protein 3

NM_020158

RRP46

1

19

M*

M

M

M

exosome component Rrp46

NM_004596

SNRPA

1

19

M

small nuclear ribonucleoprotein polypeptide A

NM_021833

UCP1

1

4

M

uncoupling protein 1

NM_000610

CD44

1

11

M

CD44 antigen (homing function and Indian blood group system)

NM_001262

CDKN2C

1

1

M

M

cyclin-dependent kinase inhibitor 2C

NM_006892

DNMT3B

1

20

M*

M*

DNA (cytosine-5-)-methyltransferase 3 beta

NM_005469

PTE1

0

20

M*

peroxisomal acyl-CoA thioesterase

NM_002827

PTPN1

1

20

M*

M*

protein tyrosine phosphatase, non-receptor type 1

NM_013375

ABT1

1

6

M

M*

M*

activator of basal transcription 1

NM_021968

HIST1H4J

1

6

M

M*

M*

M*

histone 1, H4j

NM_021063

HIST1H2BD

0

6

M*

H2B histone family, member B

NM_015966

SDBCAG84

1

20

M*

serologically defined breast cancer antigen 84

NM_006282

STK4

1

20

M*

M*

M*

serine/threonine kinase 4

NM_016359

ANKT

1

15

M

M

clone HQ0310 PRO0310p1

NM_024045

DDX50

1

10

M*

nucleolar protein GU2

NM_003714

STC2

1

5

M

M

M

stanniocalcin 2

NM_003358

UGCG

1

9

M

ceramide glucosyltransferase

NM_024813

FLJ13150

1

1

M

hypothetical protein FLJ13150

NM_052886

MAL2

1

8

M

mal, T-cell differentiation protein 2

NM_030634

ZNF436

1

1

M

zinc finger protein 436

NM_053034

ANTXR1

1

2

M

tumor endothelial marker 8 isoform 2 precursor

NM_000269

NME1

1

17

M

non-metastatic cells 1 protein

NM_018304

FLJ11029

1

17

M

M

hypothetical protein FLJ11029

NM_002194

INPP1

1

2

M

M

inositol polyphosphate-1-phosphatase

NM_014917

KIAA0976

1

1

M

M

M

netrin G1f

NM_003188

MAP3K7

1

6

M*

M*

M*

mitogen-activated protein kinase kinase kinase 7 isoform A

NM_145331

MAP3K7

1

6

M*

M*

M*

mitogen-activated protein kinase kinase kinase 7 isoform B

NM_053001

OSR2

1

8

M*

M

M

odd-skipped-related 2A protein

NM_004181

UCHL1

1

4

M

ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

NM_018268

FLJ10904

1

5

M

M*

M*

hypothetical protein FLJ10904

NM_014318

APR-2

0

17

M

M

apoptosis related protein

NM_019854

HRMT1L3

1

12

M

M

HMT1 hnRNP methyltransferase-like 3

NM_018164

FLJ10637

1

12

M

hypothetical protein FLJ10637

NM_007306

BRCA1

1

17

M

M

breast cancer 1, early onset isoform BRCA1-exon4

NM_004644

AP3B2

1

15

M

adaptor-related protein complex 3, beta 2 subunit

NM_020726

NLN

1

5

M

neurolysin (metallopeptidase M3 family)

NM_000959

PTGFR

1

1

M

prostaglandin F receptor (FP)

NM_002584

PAX7

1

1

M

paired box gene 7 isoform 1

NM_014581

OBP2B

0

9

M

odorant-binding protein 2B

NM_001063

TF

1

3

M

M

transferrin

NM_013372

CKTSF1B1

1

15

M

cysteine knot superfamily 1, BMP antagonist 1

NM_007296

BRCA1

1

17

M

breast cancer 1, early onset

NM_002913

RFC1

1

4

M

replication factor C large subunit

NM_003440

ZNF140

1

12

M

M*

M

M

zinc finger protein 140 (clone pHZ-39)

NM_002700

POU4F3

1

5

M*

M

M

POU domain, class 4, transcription factor 3

NM_000633

BCL2

1

18

M*

M

M

M

M

B-cell lymphoma protein 2 alpha

NM_000602

SERPINE1

0

7

M

M

M

serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

NM_005509

DMXL1

1

5

M

M

M

M

M

M

M*

Dmx-like 1

NM_144977

MGC27044

1

1

M

family with sequence similarity 31, member B

NM_005170

ASCL2

1

11

M

achaete-scute complex homolog-like 2

NM_014829

DDX46

1

5

M

M

M

Prp5-like DEAD-box protein

NM_133344

RAD17

1

5

M*

M*

RAD17 homolog isoform 1

NM_004675

ARHI

1

1

M

M

M

M

U

ras homolog I

NM_006557

DMRT2

1

9

M

M

M

M

doublesex and mab-3 related transcription factor 2

NM_002760

PRKY

1

Y

M*

M*

protein kinase, Y-linked

NM_006815

RNP24

1

12

M

coated vesicle membrane protein

NM_130898

AIBZIP

1

1

M

M

M

M

cAMP responsive element binding protein 3-like 4

NM_006571

DCTN6

1

8

M*

M

M

novel RGD-containing protein

NM_000451

SHOX

1

Y

M*

M*

short stature homeobox isoform a

NM_001008

RPS4Y

0

Y

M*

M*

M*

M

M

M*

M

M*

M

M*

M*

ribosomal protein S4, Y-linked Y isoform

NM_005880

DNAJA2

1

16

M

M

M

M

M

M

M

DnaJ subfamily A member 2

NM_014012

REM

1

20

M

M

M*

M*

M*

M*

RAS (RAD and GEM)-like GTP-binding

NM_001929

DGUOK

1

2

M

deoxyguanosine kinase isoform c precursor

NM_080916

DGUOK

1

2

M

M

M

M

deoxyguanosine kinase isoform a precursor

NM_014690

KIAA0773

0

7

U

U

KIAA0773 gene product

NM_153031

FLJ32063

1

2

U

hypothetical protein FLJ32063

NM_020387

RAB25

0

1

M

M

U

RAB25

NM_033304

ADRA1A

1

8

M

M

M

M

alpha-1A-adrenergic receptor isoform 4

NM_144971

MGC26641

1

Y

M

M

Homo sapiens hypothetical protein MGC26641 (MGC26641)

NM_003531

HIST1H3C

1

6

M

M

M*

H3 histone family, member C

NM_172316

MEIS2

0

15

M

M

M*

homeobox protein Meis2 isoform h

NM_016154

RAB4B

1

19

M

M

M

M

ras-related GTP-binding protein 4b

NM_003672

CDC14A

1

1

M

M

M

CDC14 homolog A isoform 1

NM_005109

OSR1

1

3

M

M

oxidative-stress responsive 1

NM_006739

MCM5

1

22

M

M

M

minichromosome maintenance deficient protein 5

NM_006254

PRKCD

1

3

M

protein kinase C, delta

NM_003639

IKBKG

1

X

U

M

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

NM_032166

TREX1

1

3

M

M

three prime repair exonuclease 1 isoform c

NM_003107

SOX4

0

6

M

M

M*

SRY (sex determining region Y)-box 4

NM_014322

OPN3

1

1

M

M

opsin 3 (encephalopsin, panopsin)

NM_033627

TREX1

1

3

M

M

M

M

M

three prime repair exonuclease 1 isoform b